PEDRO P ROCHA – Stadtman Tenure Track Investigator

Picture of Pedro Rocha lab head at NIHMy graduate studies at the Max-Planck Institute for Molecular Genetics focused on gene regulation and the role of transcriptional co-regulators during mouse development (Rocha et al. 2010). I devoted my postdoctoral training at NYU to explore the multiple ways in which nuclear organization and chromosomal interactions are important for regulation of cellular processes in development and disease.

In the Skok lab I studied the process of Class Switch Recombination in B cells and showed that DNA interactions are important to orchestrate this recombinatorial event and avoid translocations that can lead to lymphomas (Rocha et al.  2012 and 2016). I also developed techniques that were lacking in the field such as a CRISPR/dCas9-based system for live visualization of multiple loci in different colors (Fu et al. 2016) and contributed to the development of a computational pipeline for analyses of DNA interactions (Raviram et al. 2016 and github)I recently became fascinated with the world of transposon biology and have also developed tools to understand better how these invading agents can help control expression of our own genes (Raviram et al. 2018). Find full CV here .

I am very grateful for my sources of funding so far:

  • K99/R00 from NIGMS
  • Scholar Award from ASH
  • Postdoctoral Fellowship from NCC
  • Marie Curie ESR



Joyce Thompson

My long-term research interest lies in understanding how epigenetic mechanisms acting at different levels coordinate and regulate chromatin organization across development and differentiation, and their contribution to cell-fate decisions. During my graduate studies I focused on characterizing a zinc-finger protein and identified its role in modulating epigenetic mechanisms. As a postdoc in the Rocha lab, I will be studying how the chromatin is organized in the early embryo, and what factors are crucial in establishing sub-chromosomal domains and facilitating chromosomal interactions. Joyce started in October 2018.

Find Joyce’s publications here




Chakraborty_Shreeta_PictureMy longterm research goal is to unriddle how gene regulation executes a diverse repertoire of high fidelity response during cell fate decisions at the critical stages of development and differentiation. During my graduate studies my research focus was to elucidate the function of a protein called Nostrin in the different aspects of utero-placental development including trophoblast stem cell differentiation and feto-maternal angiogenesis. In the Unit on Genome Structure and Regulation at NIH, I will be exploring and investigating how a milieu of transcription factors, enhancers and promoters coordinate cell fate based upon chromatin architecture during early mammalian development. Shreeta is with us since December 2018.

Check Shreeta’s publications




Sarah Frail Postbac NIH NICHD

I graduated in May 2018 with a Bachelor in Cell Biology and Genetics from University of Maryland, College Park. Following my postbac experience I plan to apply to a biology or biochemistry PhD program.  My primary research interests lie in the investigation of nucleic acids, their complex roles and interactions in cells, and how we can manipulate those factors to treat illness. More specifically, I am interested in topics like protein-nucleic acid interactions, regulation of DNA replication and expression, and the rapidly evolving study of non-coding RNA and RNAi. Sarah is with us since July 2018.

See Sarah’s publications





I graduated in May 2018 with a Biology Bachelor of Arts from Franklin & Marshall College. My previous work examined seasonal variation in Geukensia demissa protein expression. Working at NICHD in the Unit on Genome Structure and Regulation, I hope to gain a better understanding of the underlying epigenetic mechanisms that regulate protein expression and embryonic development. After my postbac experience, I hope to enroll in a Ph.D. program to study Biochemistry, or Molecular Biology. Ariel started in October 2018.






Previous Mentees

Can be contacted for references.

Ramya Raviram, PhD

Role: PhD supervisor

Current: Postdoc at UCSD    Contact

Yi Fu, MSc

Role: Master’s Thesis Supervisor

Current: PhD student at NYU   Contact

Vincent Luo, MSc

Role: Master’s Thesis Supervisor

Current: PhD student at Mcgill University  Contact

JungHyun Kim, MSc

Role: Master’s Thesis Supervisor

Current: PhD student at University of Maryland and NIH Contact

Arafat Aljoufi, MD

Role: Master’s Thesis Supervisor

Current: PhD at Indiana University  Contact

Emily Swanzey, MSc

Role: PhD rotation Supervisor

Current: PhD at NYU  Contact